Battleborn has a Full-Fledged Campaign While Overwatch Only has Competitive Multiplayer The biggest and most noticeable difference in the titles is the amount of PvE content. Battleborn features a full campaign that can be completed solo or with friends. These aren’t just some afterthought story missions either; they are linear missions with character dialogue and objectives and big, big bosses. While they can be completed solo, I would strongly recommend playing them in a group. The waves upon waves of enemies can be a little overwhelming for one person with a non-tanky character. Overwatch simply doesn’t have any PvE or campaign option outside training mode and it doesn’t really need one. So much of the focus is on balancing team compositions and the design of the maps that any distractions from that would make the competitive multiplayer feel less polished. 
Battleborn Has an Economy In and Out of Matches While Overwatch has a Currency for Cosmetics Here is where the depth of Battleborn really starts to take place: there is a credits system for your profile which you can use to purchase loot packs for a chance to get better gear. You can sell gear you don’t want for a small fraction of its cost in hopes to buy just the right pack for your character, i.e. each race or faction will have their own set from which gear can be found. Once you find the right gear for your loadout, the in-battle economy comes into play. Most gear types must be activated in a match via crystals. The crystals are acquired through various means: farming nodes, performing objectives, or taking out enemies. Once you have acquired a good amount of crystals you now face a choice: do I activate my gear to give myself some stat boosts or do I buy structures that can help the team? It’s this sort of trade-off that makes the economy of each game unique and full of potential strategies for coordinated teams; a person will low-tier gear can still contribute to the team by building structures while his better geared teammates can buff-up early on. Overwatch has some type of currency system which can be used to purchase those cosmetic items and that’s about it. There is no in-battle economy that players need to worry about or strategize over. This simplified approach ensures that when I see a Tracer or Winston I will know exactly what their capabilities are. Heroes in Overwatch are simply avatars of the skilled players and not vessels for top-tier gear, similar to turning items off in Smash Bros.
______________________________
“Battleborn clearly has much more depth when it comes to optimizing how a hero is played while Overwatch relies on players mastering a hero’s capabilities to ascend to the next level of play.”
What the most fascinating part to me is how both games take a completely different philosophy to what gear, if any, players have access to and both are fairly well balanced. Battleborn clearly has much more depth when it comes to optimizing how a hero is played while Overwatch relies on players mastering a hero’s capabilities to ascend to the next level of play. 
Battleborn Has a Talent Tree While Overwatch has Hero Switching I’ve saved what I believe to be the most defining difference for last. Firstly, all Battleborn heroes have an associated talent tree. This tree is filled out during each match, much like you would pick talents or items in many MOBAs. Each tree starts out with 20 talents, 2 mutually exclusive choices per level. Each side of the tree caters to a specific playstyle and can completely upgrade the effectiveness of your skills. Some talents turn your skills into high-risk-high-reward skillshots while others can nerf damage for easier hit chance. There don’t seem to be many definitive picks for skills as long as you can adapt your playstyle. It all comes down to what will synergize best for the circumstances in the exact moment. Overwatch doesn’t have any sort of leveling up mechanic during battles. Instead you are allowed to change your hero as many times as you want during a match. This is actually quite more analogous to picking talents in Battleborn than you might think; instead of picking talents to counter enemy heroes, you can rotate heroes that counter enemies. Any good Overwatch player will tell you it’s imperative to know which heroes counter which. If you refuse to play more than one or two heroes, you will have a hard time keeping a positive win percentage. 
Battleborn allows for you to become proficient with one or two heroes provided you understand which talents to take in the right situations; Overwatch simply requires you to be proficient with half the roster in order to stay competitive. Battleborn will release on May 3, 2016 for Microsoft Windows, PlayStation 4 and Xbox One. Overwatch is scheduled to be released on May 24, 2016 for Microsoft Windows, PlayStation 4, and Xbox One.